Side effects of axitinib targeted drug

Axitinib is used alone to treat advanced renal cell carcinoma (RCC, a cancer that starts in cells in the kidneys) in patients who have not been successfully treated with other drugs. Axitinib is used in combination with avelumab (Bavencio) or pembrolizumab (Keytruda) to treat advanced renal cell carcinoma. Axitinib belongs to a class of drugs called kinase inhibitors. It works by blocking the action of abnormal proteins that signal cancer cells to multiply. This helps slow or stop the spread of cancer cells.

Axitinib is available in tablet form. Tablets should be swallowed whole with a glass of water, whether or not with food. Do not break, crush, or chew tablets. If you forget to take your dose or if you vomit after taking it, do not take another dose. Take your next dose at your usual time. If you have trouble swallowing your medicine, contact your pharmacist or care team.

The most common side effects of axitinib (occurring in more than 20% of patients) are diarrhea, high blood pressure, fatigue, dysphonia, nausea, vomiting, decreased appetite, loss of weight loss, palmoplantar erythrodysesthesia syndrome (rash and numbness on the palms and soles of the feet), hemorrhage (bleeding), hypothyroidism (low thyroid function), protein in the urine, cough, and constipation.

Axitinib is currently on the market in China and has been included in my country's medical insurance reimbursement items. The specifications of the domestically marketed original drug are 5mg*28 tablets, and the price is about 6,000 yuan. After medical insurance reimbursement, it is about 2,000yuan. The reimbursement ratio of medical insurance will vary depending on the region. You can consult the local medical insurance bureau for specific reimbursement ratios. In addition, we can learn about the price of axitinib abroad. The original drug specification of axitinib is the same as the domestic version, and the price is around 6,000 yuan. There are also related generic drugs of Axitinib on the market overseas. The specification of Bikang Pharmaceutical in Bangladesh is 5mg*60 tablets, and the price is 1,800 yuan.