Must-read for patients: Overview of basic information in the package insert for trolagliptin

1. Common name: Trelagliptin , Trelagliptin

Product name: Zafatek

Other names: Trilagliptin, trolagliptin succinate

2. Who can take trotagliptin? Indications?

Trelagliptin (Trelagliptin) inhibits DPP-4 (an enzyme that degrades incretin hormones, which maintain blood sugar levels constant), thereby stimulating insulin secretion when blood sugar rises, thereby improving blood sugar control. Often used to treat type 2 diabetes. Tretagliptin can also be used when first-line treatment with metformin fails to achieve the expected glycemic target.

3. What are the side effects of trotagliptin?

The most commonly reported adverse reactions of trolagliptin include cold sweats, convulsions, decreased consciousness, blisters, rash, pruritus, vomiting, abdominal pain, and bloating.

4. How should you take trotagliptin?

The dosage plan prescribed by doctors for patients is: Generally speaking, for adults, take 2 tablets (100 mg trolagliptin) at a time, once a week, on fixed days of the week. The dose may be reduced based on the degree of renal function in patients with moderate or severe renal impairment. Follow instructions strictly. If the patient misses a dose, take the missed dose as soon as possible and then follow the regular weekly dosing schedule. Two doses should not be taken at one time. If the patient accidentally takes more than the prescribed dose, consult a doctor or pharmacist. Do not stop taking your medicine unless your doctor directs you to do so.

5. How to store troagliptin?

Trelagliptin is available in tablet form. Keep out of the reach of children and store at room temperature (1 to 30 degrees Celsius) away from direct sunlight, high temperature, and moisture. Discard the remainder and do not give this medication to others.

6. How does troagliptin work?

Glucagon is a peptide hormone produced by thealpha cells of the pancreas. Tretagliptin increases the concentration of glucose in the blood. Incretins are a group of metabolic hormones that stimulate a drop in blood sugar levels. They also inhibit glucagon release from pancreatic alpha cells. DPP-4 plays a major role in glucose metabolism. Trelagliptin is responsible for the degradation of incretin and the increase in blood glucose levels.

7. Precautions when taking troagliptin

1. Strictly follow the instructions for diet/exercise therapy:

2. If symptoms of hypoglycemia occur (hunger, cold sweat, pale face, easy fatigue, limb tremors, twitching, decreased consciousness), please take carbohydrate-containing foods or general sugar;

3. If the patient takes this drug andalpha-glucosidase inhibitors (drugs that delay sugar absorption such as acarbose, voglibose and miglitol) at the same time, please take glucose;

4. This drug may cause acute pancreatitis (persistent severe abdominal pain and vomiting are the initial symptoms). If these symptoms occur, please consult your doctor immediately.

5. Since the drug is taken once a week, the effect will continue after stopping the drug. Please pay attention to the occurrence of adverse reactions or blood sugar levels. If the patient feels abnormally, please consult a doctor or pharmacist immediately.

6. Pay special attention to the fact that hypoglycemia may cause accidents when working at heights or driving a car.

7. It is necessary to measure blood sugar levels regularly. Follow your doctor's instructions for testing.

8. Inform your family about the preventive measures for hypoglycemia and ensure that you inform your family and those around you that you are taking anti-diabetic drugs.