How much does it cost to buy a box of entrectinib in 2024?

Entrectinib (Entrectinib) is available as capsules, suspension capsules, or oral pills. Usually taken once daily, with or without food. Entrectinib is used to treat adults with non-small cell lung cancer (NSCLC) that has spread to other parts of the body. It is also used to treat certain types of solid tumors in adults and children 1 month and older that cannot be treated with surgery or have spread to other parts of the body and worsened after treatment with other chemotherapy drugs.

Entrectinib belongs to the kinase inhibitor class of drugs. It prevents cancer cells from multiplying by blocking the action of abnormal proteins. This helps stop or slow the spread of cancer cells. Patients need to take entrectinib at about the same time each day and do not take more or less or more often than prescribed by their doctor. Do not chew or crush capsule contents or granules. If a patient vomits immediately after taking entrectinib, take another dose as soon as possible. If serious side effects occur, your doctor may temporarily or permanently stop treatment or reduce the dose.

The original drug of entrectinib is marketed in China in the form of capsules and is included in the scope of medical insurance reimbursement. Patients who meet the indications can use medical insurance for reimbursement. Common specifications include100mg*30 capsules, 2 00mg*90 pills, the price per box may be more than 20,000 RMB; while the European version of the original drug marketed overseas is more expensive, and the price per box of 200mg*90 pills may be more than 40,000 RMB (the price may fluctuate due to exchange rates). At present, entrectinib generic drugs are also sold overseas, and their drug ingredients are basically the same as those of the original drug. For example, the same specifications are produced by Laos pharmaceutical factories, and the price per box may be more than 1,000 to 6,000 yuan (the price may fluctuate due to exchange rates).