What diseases is cabozantinib/cazantinib used to treat?

Cabozantinib is a multi-target broad-spectrum anticancer drug that is widely used in the treatment of a variety of solid tumors. Its therapeutic effect has been verified in a variety of cancers, and it is known as the "Taiwan Balm among targeted drugs."

1.Thyroid cancer: Cabozantinib has shown significant efficacy in the treatment of thyroid cancer, especially differentiated thyroid cancer (DTC). Clinical trials have shown that cabozantinib can significantly prolong the progression-free survival and reduce the risk of disease progression or death in patients with radioactive iodine-refractory DTC who have previously received VEGFR targeted therapy. Additionally, it is used to treat progressive, unresectable, or metastatic medullary thyroid cancer.

2.Kidney cancer: Cabozantinib also has a significant effect in the treatment of kidney cancer, especially for patients with advanced renal cell carcinoma (RCC) who have undergone anti-angiogenic therapy. Its multi-target inhibitory properties allow it to target multiple growth and metastasis mechanisms of renal cancer.

3.Liver cancer: In the treatment of liver cancer, cabozantinib, as a second-line treatment drug, can prolong the survival of patients and improve progression-free survival and objective response rate. Cabozantinib has also shown modest efficacy in patients with advanced hepatocellular carcinoma who have progressed after other standard systemic therapies.

However, it's important to note that while cabozantinib works well in a variety of cancer treatments, each patient's response may vary. Therefore, before using cabozantinib, a personalized treatment plan should be developed based on the patient's specific situation and the doctor's recommendations.