How much is the latest price of acotinib/acabrutinib in 2024

Acotinib (also known as acalabrutinib) has been officially launched in China and has been included in the medical insurance system, providing treatment options for the majority of patients. At present, the price of this drug in China is roughly between 3 yuan and 5 yuan. Although it is expensive, considering its efficacy and the actual needs of patients, this price range still has certain market competitiveness.

It is worth mentioning that Yaobin International in Bangladesh and ASEAN Pharmaceuticals in Laos also have regular and legal supplies of acotinib generics. These generic drugs are highly consistent with the original drugs in terms of drug ingredients, ensuring that patients receive similar therapeutic effects as the original drugs. The price is more affordable, with the latest price ranging from 4000 yuan to 6000 yuan, providing patients with more diversified treatment options.

Acotinib, as a second-generation selective Bruton's tyrosine kinase (BTK) inhibitor, has a unique pharmacological mechanism of action. It can covalently bind to BTK, inhibit its activity, and then block the signaling pathways leading to cell proliferation, transport, chemotaxis and adhesion in B cells, thereby achieving the purpose of treating B cell malignant tumors.

Acotinib is approved for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. According to the results of a Phase II clinical study of ACE-LY-004, acotinib showed significant efficacy in adult patients with MCL. After long-term follow-up, the objective response rate was as high as 81%, of which 48% of patients achieved complete remission. At the same time, the drug also shows good safety characteristics, such as reducing the incidence of adverse reactions such as atrial fibrillation.

For patients who need to purchase acotinib, we recommend that you choose the appropriate drug based on your needs and financial situation. If you choose to purchase generic drugs, be sure to purchase them through regular overseas channels to ensure the quality and safety of the drugs.