How much does it cost to buy a box of fenelidone in 2024?

Finerenone (Finerenone, sold overseas under the brand names Kerendia and Firialta, is a drug used to reduce the risk of kidney function decline, kidney failure, cardiovascular death, non-fatal heart attack and heart failure hospitalization in adults with chronic kidney disease associated with type 2 diabetes. Fenelidone is a nonsteroidal mineralocorticoid receptor antagonist (MRA) administered orally.

Fenelidone is used to reduce the risk of serious kidney and heart problems (such as kidney function decline, end-stage renal disease, cardiovascular death, heart attack, and hospitalization for heart failure) in people with chronic kidney disease associated with type 2 diabetes. Common side effects include hyperkalemia (high potassium), hypotension, and hyponatremia (low sodium). Compared with currently available aldosterone antagonists (such as eplerenone and spironolactone), fenelinone has a lower relative affinity for other steroid hormone receptors, which should result in fewer side effects such as breast enlargement, impotence, and low libido. Fenelidone blocks mineralocorticoid receptors, making it a potassium-sparing diuretic.

The original drug of fenelidone tablets has been launched in China, and the drug has also been included in the reimbursement scope of Class B medical insurance. Common drug specifications include 14 tablets of 10mg and 7 tablets of 20mg, with a price of approximately several hundred yuan per box. Overseas, the price of this kind of medicine is relatively expensive, such as the American version, European version and Japanese version, the price of 100 tablets may be as high as about 3,000 yuan (the price may fluctuate due to exchange rate changes). In addition, generic drugs are also sold in overseas markets, and their ingredients are basically the same as the original drugs. For example, a 30-piece package produced in Laos costs about 200 yuan, but the price may also fluctuate due to exchange rates.