How much does Cabozantinib cost? Is it covered by medical insurance?

Cabozantinib is available in two forms, one is a capsule form (Cometriq), which is mainly used to treat medullary thyroid cancer; the other is a tablet form (Cabometyx), which is used for the treatment of renal cell carcinoma, hepatocellular carcinoma and differentiated thyroid cancer. Because the Cometriq and Cabometyx brands have different formulations, they are not interchangeable.

Cabozantinib is a tyrosine kinase inhibitor that inhibits the activity of multiple receptor tyrosine kinases, including vascular endothelial growth factor receptor (VEGFR), hepatocyte growth factor receptor (MET) and microvessel-associated protein receptor (RET). These receptors play a key role in the growth, metastasis and angiogenesis of cancer. Cabozantinib's mechanism of action is to block the signaling of these receptors, thereby inhibiting the growth and spread of tumor cells.

Although cabozantinib has achieved remarkable therapeutic results, it is also accompanied by a series of side effects. Common side effects include diarrhea, nausea, vomiting, decreased appetite, weight loss, fatigue and other gastrointestinal and systemic symptoms. In addition, hand-foot skin reaction, hypertension, taste disorder, etc. may also occur. The degree and incidence of these side effects may vary in different patients, so when using cabozantinib, the patient's condition needs to be closely monitored and the treatment plan adjusted according to the specific situation.

Currently, cabozantinib is not yet available in the Chinese market, so patients in need cannot purchase it directly from domestic hospitals. It is reported that the original research version and various generic versions of cabozantinib are available for purchase in overseas markets. The original research version of tablets is priced at approximately 35,000 yuan, while the capsule version is approximately 46,000 yuan. It is particularly worth mentioning that the original research version of tablets produced in Türkiye is particularly outstanding in terms of cost performance. At the same time, the price of the generic version of cabozantinib available overseas is relatively affordable, ranging from RMB 800 to RMB 7,600, providing patients with a variety of choices. If you have more questions about cabozantinib, it is recommended to consult a regular overseas medical consulting company.