How much does osimertinib cost, and is it included in medical insurance reimbursement?

Osimertinib (Tagrisso) , chemical name AZD-9291, is a highly efficient and selective EGFR mutant inhibitor. As a third-generation EGFR tyrosine kinase inhibitor, osimertinib plays a pivotal role in the field of cancer treatment, especially in the treatment of non-small cell lung cancer (NSCLC).

The emergence of osimertinib has brought new treatment options to patients with non-small cell lung cancer, especially those who have developed resistance after treatment with first- or second-generationEGFR inhibitors. Its unique mechanism enables it to exert a powerful inhibitory effect against the T790M gene mutation. This gene mutation often occurs after long-term use of other EGFR inhibitors such as Iressa, Kemena or Tarceva, causing these drugs to fail. Osimertinib not only has significant efficacy against these drug-resistant cancer cells, but also has relatively mild side effects, which is a very important advantage clinically.

The recommended dose of osimertinib is 80 mg daily and needs to be taken continuously until the disease progresses or the patient cannot tolerate its side effects. It is worth mentioning that osimertinib is not affected by food and can be taken with food or on an empty stomach, which provides patients with medication flexibility. However, to ensure optimal absorption and effectiveness of the medication, it is recommended to swallow the tablets whole with water.

In addition, osimertinib has been widely used and recognized worldwide. Although it is an imported drug, it has become one of the important choices for the treatment of non-small cell lung cancer in countries and regions such as China. Its efficacy is remarkable, not only extending the survival period of many patients, but also significantly improving their quality of life.

Osimertinib is currently on the market in China and has been included in my country’s medical insurance reimbursement items. A box of 80mg*30 pills costs about 5,000 yuan after reimbursement by medical insurance. Osimertinib currently has related generic drugs in Laos, Bangladesh and other countries, with specifications of 80mg*30 tablets. Most of the generic versions on the market are between 600-1,000 yuan. The price of Lucius in Laos is as low as about 590 yuan, and the price of Beacon Pharmaceutical in Bangladesh is as high as about 2,400 yuan. If you have more questions about osimertinib, please consult a regular overseas medical consulting company.