What are the side effects of Valganciclovir/Valganciclovir?

Valganciclovir is an antiviral drug used to treat and prevent cytomegalovirus (CMV) infection in high-risk patients, such as immunocompromised patients. Although valganciclovir is well tolerated clinically, like other drugs, there are some side effects that may cause intolerability.

After valganciclovir is launched on the market, it is available in two forms: tablets and oral solution preparations. For adult patients, valganciclovir tablets are often taken, and clinical studies have shown that ≥20% The most common adverse reactions reported in adult patients for at least one indication were diarrhea, pyrexia, fatigue, nausea, tremor, headache, insomnia, urinary tract infection, and vomiting; laboratory abnormalities reported were neutropenia, anemia, leukopenia, and thrombocytopenia.

For pediatric patients, valganciclovir oral solution or tablets may be taken. In clinical studies, ≥20% of pediatric solid organ transplant recipients reported at least one of the most common adverse reactions for at least one indication: diarrhea, fever, upper respiratory tract infection, urinary tract infection, vomiting and headache; laboratory abnormalities reported were neutropenia and leukopenia.

In addition, in the post-marketing cases of valganciclovir, a few patients experienced adverse events such as allergic reactions, agranulocytosis, and neutropenia. The occurrence of these side effects may be related to individual differences, drug interactions with other drugs, and the patient's overall health. Therefore, when using valganciclovir, physicians will assess the risks and benefits based on the patient's condition and monitor the patient's treatment response and occurrence of adverse events.