What are the side effects of Leqselvi (Deuruxolitinib)?

Leqselvi (Deuruxolitinib) is a Janus kinase (JAK) inhibitor primarily used to treat severe alopecia areata in adults. A variety of side effects may occur while taking Leqselvi. Common adverse reactions include headache, acne, nasopharyngitis, elevated blood creatine phosphokinase, hyperlipidemia, fatigue, weight gain, lymphopenia, thrombocytosis, anemia, skin and soft tissue infections, neutropenia, and herpes.

A warning box is specifically marked on the Leqselvi product label to remind patients of the risk of serious infections, higher all-cause mortality, increased risk of malignancies (such as lymphoma and lung cancer), higher incidence of major adverse cardiovascular events (MACE), and higher risk of thrombosis. These warnings and precautions require patients and doctors to pay close attention, handle them promptly and take corresponding measures.

In addition,Leqselvi also has some potentially serious side effects, such as gastrointestinal perforation and certain laboratory abnormalities. While using Leqselvi, patients should go to the hospital for regular check-ups to ensure their physical condition is stable, and adjust their medication regimen according to the doctor's recommendations. Any discomfort or abnormality should be reported to the doctor in time so that the treatment plan can be adjusted promptly to ensure the health and safety of the patient.

In short, when using Leqselvi to treat alopecia areata, patients should pay close attention to the side effects and warning information of the drug, and cooperate with the doctor's guidance and monitoring to ensure safe and effective treatment. Only by using Leqselvi rationally under the guidance of a doctor can the occurrence of adverse reactions be minimized and the expected therapeutic effect achieved.