How many boxes of capmatinib can be taken a month and how much does it cost to take it?

Capmatinib (Capmatinib) contains the active substance capmatinib and is a drug used to treat adults with a type of cancer called non-small cell cancer (NSCLC). When the cancer is advanced, the cells undergo specific genetic mutations (changes) that cause "mesenchymal-to-epithelial transition factor gene exon 14 (METex14) skipping." This means that the cancer cells produce an abnormal form of a protein called MET because part of exon 14 of the MET gene is not used. Capmatinib is used when patients require further treatment after receiving immunotherapy or platinum-based chemotherapy, or both.

Capmatinib is only available by prescription, and treatment should be started and supervised by a doctor experienced in the use of cancer drugs. Before starting treatment, patients should undergo testing to confirm the METex14 skipping mutation in their cancer. Capmatinib is available as oral tablets. The recommended dose is 400mg twice daily, for a total of 800mg per day. Based on this dose calculation, the total dose required by the patient in one month (30 days) is: 800 mg/day * 30 days = 24,000 mg. Treatment with capmatinib can be continued as long as the patient is benefiting from it.

Due to the different specifications and prices of each box of capmatinib, the calculation may be based on two situations: the specification of the original drug currently sold in Hong Kong, China is 200mg*60 tablets per box and the price exceeds 30,000 yuan, so the monthly cost is approximately more than 60,000 yuan. At the same time, comparatively cheaper generic capmatinib drugs are also sold overseas. For example, each box of 200mg*56 tablets of the drug produced by a Laos pharmaceutical factory is priced at more than 3,000 yuan. The approximate cost for one month is more than 6,000 yuan. The pharmaceutical ingredients of generic capmatinib are basically the same as those of the original drug, and prices may vary due to market fluctuations and regional differences.