How much does a box of molotinib/mometinib cost in 2024?

Momelotinib belongs to the kinase inhibitor class of drugs. It works by blocking the activity of abnormal proteins, which are signals for cancer cell reproduction, which helps prevent or slow the spread of cancer cells. Molotinib is mainly used to treat certain types of myelofibrosis (MF; a type of bone marrow cancer in which the bone marrow is replaced by scar tissue, leading to reduced blood cell production) in adults who have anemia.

Molotinib is an oral tablet that is usually taken once a day with or without food. Take molotinib at about the same time each day and do not take more or less often than prescribed by your doctor. Swallow the tablets whole; do not cut, chew, or crush them. The doctor will order blood tests before and during treatment to see how the patient is affected by the drug. Your doctor may reduce your molotinib dose during treatment or may recommend stopping molotinib temporarily or permanently. This depends on how well the drug works for the patient, lab test results, and whether there are any side effects.

The original drug molotinib is not currently on the market in China, so it cannot be included in medical insurance. The U.S. version of the original drug currently on the market overseas, the common specifications are:100mg*30 tablets, 150mg*30 tablets, 200mg*30 tablets. The price of each box may be 200,000 yuan (the price may fluctuate due to the exchange rate), which is very expensive. In addition, the first generic drug of molotinib has been developed and sold, and its drug ingredients are basically the same as the original drug. For example, the specifications produced by Lucius Pharmaceuticals in Laos are 100mg*30 tablets, and the price per box may be more than 2,000 yuan (the price may fluctuate due to the exchange rate), and the price is relatively cheap. For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.