How much does a box of dabrafenib/dabrafenib cost in 2024?

Dabrafenib belongs to a class of drugs called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells. Dabrafenib is taken orally in capsule form, usually taken twice daily on an empty stomach, 1 hour before or 2 hours after a meal. Do not stop taking dabufenil without consulting your doctor.

Dabrafenib is used alone or in combination with trametinib (Mekinist) to treat certain types of melanoma (a type of cancer). It is also used in combination with trametinib to prevent certain types of melanoma from coming back after surgery; or in combination to treat certain types of non-small cell lung cancer and thyroid cancer; it is also used to treat certain types of solid tumors in adults and children 6 years or older; and to treat certain types of glioma (a cancerous brain tumor) in children 1 year or older.

The original version of dabrafenib has been launched in China and is included in medical insurance. There are two main common dosage forms, namely50mg*120 capsules and 75mg*120 capsules. The price of each box may be in more than RMB 10,000. Dabrafenib is also sold overseas. The original Turkish version of 75mg*120 capsules is priced at more than 7,000 yuan per box (the price may fluctuate due to exchange rates). In addition to the original drug, there are also a variety of generic versions of dabrafenib on the overseas market, and their pharmaceutical ingredients are basically the same as the original drug. For example, the price of the same specification sold by a Lao pharmaceutical factory may be more than 2,000 yuan per box (the price may fluctuate due to exchange rates).