Brief description of instructions for use of Bangladeshi version of baricitinib generic drug

Baricitinib (Baricitinib) is an oral, selective JAK1 and JAK2 inhibitor. It is mainly used to treat adult patients with moderately to severely active rheumatoid arthritis who are ineffective or intolerant to one or more disease-modifying antirheumatic drugs (DMARDs), as well as for the systemic treatment of severe alopecia areata in adults. The Bangladeshi version of baricitinib generic drug is an alternative to the original drug, and its instructions for use are crucial for patients to use the drug correctly.

1. Drug information

Drug name: Baricitinib Tablets (Baricitinib Tablets)

Manufacturer: Many pharmaceutical companies in Bangladesh (such as General Pharmaceutical Company, Yaopin International Pharmaceutical Company)

Specification: usually2mg

Price: It varies depending on the version. For example, the universal version costs about 200 per box, and the Yaopin international version costs about 500 per box.

2. Indications, usage and dosage

1. Indications:

1) Rheumatoid arthritis: The recommended dose is 2 mg taken orally once a day, before or after meals. It can be used alone or in combination with methotrexate or other nonbiological DMARDs.

2) Adults with severe alopecia areata: The recommended dose is 2 mg taken orally once a day. If the response is insufficient, it can be increased to 4 mg once a day.

3) Adult COVID-19 patients: The recommended dose is 4 mg orally once daily, with or without food, for 14 days or until discharge, whichever occurs first. For patients who cannot swallow tablets, alternative dosing may be used

2. Usage and dosage:

1) Patients take it once a day at a fixed time.

2) Baricitinib can be taken with or without food.

3. Precautions

1. Contraindications: It is prohibited for those who are allergic to baricitinib or any excipients; pregnant women, lactating women, patients with liver and kidney damage, and infected patients should use with caution.

2. Adverse reactions: Upper respiratory tract infection, headache, stomach discomfort, fatigue and other adverse reactions may occur. Serious adverse reactions require prompt medical treatment.

3. Monitoring and adjustment: During treatment, liver and kidney function, blood routine and other indicators need to be monitored regularly, and the dosage should be adjusted according to the doctor's recommendations.

4. Storage and disposal

Baricitinib tablets should be stored in a dry, cool, dark place and kept out of reach of children.

5. Special tips

1. Baricitinib is a prescription drug and must be purchased and used with a doctor’s prescription.

2. When using the Bangladeshi version of the generic version of baricitinib, patients should read the instructions carefully and take the medication under the guidance of a doctor.

3. If any discomfort or suspected adverse drug reaction occurs, stop taking the medication immediately and seek medical advice.

In short, the Bangladeshi version of the baricitinib generic is an alternative to the original drug, and its instructions for use provide detailed medication guidance, precautions, adverse reactions and other information. Patients should fully understand this information before taking the medicine and use the medicine safely and effectively under the guidance of a doctor.