Is ixazomib/enleri produced in India? Is it expensive?

Ixazomib/Ixazomib is an oral organic platinum drug mainly used for the treatment of multiple myeloma. Its indications mainly include use in combination with other treatment options, such as lenalidomide and dexamethasone, in patients with relapsed or refractory multiple myeloma who have received at least one round of therapy. Ixazomib inhibits the function of the proteasome and interferes with the intracellular protein degradation process, thereby promoting the apoptosis of tumor cells and showing good anti-tumor activity.

In terms of drug production, according to the relevant information currently on the market, generic drugs of ixazomib have been put on the market for sale. The first generic drug was launched by Lucius Pharmaceuticals in Laos. At present, relevant pharmaceutical factories in India do not currently produce its original drugs or generic drugs, but they may be purchased locally as imported drugs in the Indian market. This suggests that despite the increasing use of ixazomib globally, generic availability remains limited in some specific regions, particularly in Asia.

Regarding price, ixazomib is usually priced higher, which is closely related to its research and development costs, market demand, production technology and other factors. In some countries or regions, patients may need to bear a greater financial burden. Therefore, when patients use ixazomib, in addition to considering the efficacy of the drug, they also need to carefully evaluate their own financial situation.

The domestically marketed ixazomib original drug has been included in Class B medical insurance, and capsules of various sizes are available for patients to choose from. But unfortunately, the price per box exceeds 10,000 yuan, which is unaffordable for many patients. In the international market, the original drug of Ixazomib is also expensive, with each box selling for more than US$10,000. But for the generic version, taking 4mg*3 capsules as an example, the price per box may be less than 1,000 yuan (the specific price is affected by exchange rate fluctuations), which undoubtedly provides patients with more choices.