How much does a box of ritexitinib cost in China in 2024?

Ritlecitinib (Ritlecitinib) is a covalent kinase inhibitor indicated for the treatment of severe alopecia areata in adults and adolescents 12 years and older. Alopecia areata is an autoimmune disease caused by the immune system attacking hair follicles, causing hair loss. It is characterized by patchy hair loss, almost always involving the scalp. Ritlecitinib contains ritlecitinib, a highly selective covalent kinase inhibitor for Janus kinase 3 (JAK3). Ritexitinib is thought to act by blocking cytokine signaling and the cytolytic activity of T cells, which is related to the pathogenesis of alopecia areata.

Ritinib is an oral capsule that is relatively convenient to take. It is usually taken once daily. The capsule form is easy to swallow. Swallow the capsules whole with or without food; do not split, chew or crush them. However, patients should also pay attention to drug interactions and possible side effects when using it. Common adverse reactions include headache, diarrhea, acne, rash, urticaria, folliculitis, fever, atopic dermatitis, dizziness, increased blood creatine phosphokinase, herpes zoster, reduced red blood cell count and stomatitis, etc., as well as the safety of medication in special groups such as pregnant and lactating women, elderly patients and patients with liver damage.

The original drug Ritexitinib has been approved for marketing in the country, but it has not yet been included in medical insurance. Common specifications are50mg*30 capsules, and each box may be sold for more than 3,000 yuan. The European version of the original medicine sold overseas may cost more than 10,000 yuan per box (the price may fluctuate due to exchange rates). At the same time, generic drugs of Ritexitinib have also been produced and sold overseas. Their drug ingredients are basically the same as the original drugs sold domestically and abroad. For example, each box produced by a Laos pharmaceutical factory may sell for more than 1,000 yuan.