What medicine should you take for ulcerative colitis?

Ulcerative drug treatment for ulcerative colitis (UC) is a comprehensive and individualized process that needs to be determined based on the patient's specific condition, symptom severity, and physician guidance. Here are some commonly used therapeutic drugs and their mechanisms of action:

For patients with active ulcerative colitis, aminosalicylic acid preparations, such as mesalazine enteric-coated tablets or sulfasalazine, are preferred for mild patients. These drugs can reduce intestinal inflammation. If the disease is in the distal colon, suppositories may also be an option. For moderate and severe cases, in addition to aminosalicylic acid preparations, hormones such as hydrocortisone or methylprednisolone may be needed to control the disease. In particular, methylprednisolone, as an intravenous drip drug, is suitable for patients with severe and rapid disease progression.

Immunosuppressants, such as azathioprine or cyclosporine, are suitable for patients who are refractory to or dependent on hormone therapy. These drugs suppress the immune system's overreaction, thereby reducing inflammation. Biological agents such as adalimumab have better effects on moderate to severe patients who are ineffective in traditional treatments. They can specifically inhibit the inflammatory response.

In addition, intestinal probiotics such as Bifidobacterium and Lactobacillus acidophilus are also options for auxiliary treatment. They can regulate intestinal flora and help improve the intestinal environment.

For the remission phase of ulcerative colitis, the main treatment drugs are aminosalicylic acid preparations, but the dose will be reduced compared with the active phase. At the same time, patients also need to undergo regular colonoscopies to monitor their condition and prevent cancer.

In general, medical treatment of ulcerative colitis needs to comprehensively consider the patient's specific situation and be carried out under the guidance of a doctor. Patients should also pay attention to dietary and lifestyle adjustments to assist treatment and promote recovery.

Reference materials:https://www.nhs.uk/conditions/ulcerative-colitis/

(Click to view the introduction of drugs for the treatment of ulcerative colitis. For specific drug details, please click for one-on-one consultation.)