How much will the medical insurance price of lorlatinib be in 2024?

Lorlatinib is a third-generation ALKtyrosine kinase inhibitor (TKI), developed by Pfizer of the United States. It is mainly used for For the treatment of ALK-positive or ROS1-positive advanced non-small cell lung cancer (NSCLC). Compared with the first and second generation ALK inhibitors, lorlatinib not only can effectively deal with multiple drug-resistant mutations of the ALK gene, but also has significant efficacy against central nervous system metastasis. Its mechanism of action is to selectively inhibit the tyrosine kinase activity of ALK and ROS1, blocking cancer cell signal transduction, thereby controlling the growth and spread of tumors.

Domestic price and medical insurance information

Larlatinib has been launched in China and has been included in the national medical insurance directory. Although the price has been reduced after medical insurance, patients still have to pay a high fee, about 10,000 to 20,000 yuan per month. For specific prices and reimbursement ratios, you need to consult the local hospital or medical insurance agency.

Foreign prices

In foreign markets, the price of lorlatinib varies by region:

1.Original Turkish medicine: about more than 7,000 yuan, relatively low price.

2.Original drugs from Hong Kong, China: The price is about 30,000 yuan, and the cost is relatively high.

In addition, generic drug versions are mainly from Laos and Bangladesh. These drugs are low-priced, ranging from about more than one thousand yuan to several thousand yuan per month, providing patients with more choices.

Lorlatinib has become an important treatment option for patients with ALKpositive NSCLC due to its strong potency and good tolerance. For patients with a greater financial burden, generic drugs provide an affordable alternative, but they need to ensure that they are purchased from formal channels to ensure the quality of the drugs.

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Reference materials

1.Pfizer official website:https://www.pfizer.com

2.National Health Insurance Administration of China:http://www.nhsa.gov.cn