Arynta (Lisdexamfetamine) instructions in Chinese

[drug name]

Common name: lisdexamfetamine dimesylate oral solution (lisdexamfetamine dimesylate oral solution)

Product name:Aryta

【Indications】

1. For the treatment of attention deficit hyperactivity disorder (ADHD) in adults and children aged 6 years and above.

2. For the treatment of moderate to severe binge eating disorder (BED) in adults.

【Pharmacological effects】

Aryta's active ingredient, lisdexamfetamine, is metabolized in the body to dextroamphetamine. Its mechanism is mainly by blocking the reuptake of dopamine and norepinephrine and increasing neurotransmitter levels in the prefrontal cortex, thereby improving attention, executive function and impulse control. It is a central nervous system (CNS) stimulant.

【Dosage Forms and Specifications】

Aryta is an oral solution formulated to provide convenience for patients who have difficulty swallowing solid dosage forms or who prefer liquid dosage forms. This is the first approved lisdexamethasone dimesylate oral solution.

【Usage and Dosage】

1. ADHD (adults and children 6 years and above)

Initial dose: daily morning 30mg; titration: increase by 10mg or 20mg weekly;

Recommended dose: daily 30mg-70mg; maximum dose: 70mg daily.

2. BED (Adult)

Initial dose: daily morning 30mg; titration: 20mg weekly;

Recommended dose: daily 50mg-70mg; maximum dose: 70mg daily.

3. Precautions: Take orally once a day in the morning. Avoid taking medications at night to reduce the risk of insomnia.

[Common adverse reactions]

1. ADHD (children and adults aged 6-17): anorexia, anxiety, decreased appetite, weight loss, diarrhea, dizziness, dry mouth, irritability, insomnia, nausea, epigastric pain, and vomiting.

2. BED (adults): dry mouth, insomnia, decreased appetite, accelerated heart rate, constipation, tension, and anxiety.

【Drug Storage】

Store at Room temperature 20°C-25°C (68°F-77°F). Keep container tightly closed. Store in a safe place (such as a locked cupboard). The remaining solution should not exceed 30 days after opening the bottle and must be discarded.

Reference materials:https://www.drugs.com/arynta.html