地拉罗司是哪里产的?
Where is (Enrig) produced? The manufacturer of Deferasirox (Enrego) is Novartis Pharmaceuticals Co., Ltd. of Switzerland. In 1996, two century-old companies on the Rhine River in Switzerland, Ciba-Geigy and Sandoz, announced their merger to form Novartis. Novartis focuses on the growth areas of pharmaceuticals and healthcare, with a diversified business portfolio of innovative medicines, preventive vaccines and diagnostics, as well as consumer healthcare products to best meet the needs of patients and society. Novartis is a leading company in the above four fields.
The U.S. Food and Drug Administration (FDA) approved a new indication for deferasirox (Enriga) on January 23 for the treatment of chronic iron overload in patients 10 years and older with non-transfusion-dependent thalassemia (NTDT). The launch of deferasirox has also attracted much attention from patients.
Deferasirox (Enrig) is the first oral iron-removing agent approved by the U.S. FDA for routine use. It is approved for use in patients ≥2 years old with chronic iron overload caused by blood transfusion. In Europe, it is recommended as a first-line drug for thalassemia iron overload patients over 6 years old. Clinical studies are currently underway in China; Phase II and III clinical trials and pharmacokinetic studies have shown that it has good safety and tolerability. It can significantly reduce the iron load on the heart and liver and is easily accepted by patients. At the same time, it also has pharmaceutical properties such as antifungal (such as Mucor that grows in an iron-rich environment), anti-cell proliferation, anti-malarial, anti-oxidative stress damage, anti-cytotoxic-induced apoptosis, etc.; it can be used for the treatment of secondary hemochromatosis, porphyria cutanea tarda and other diseases.
Patients should pay attention to the following when using (Enrige): use with caution by pregnant women and children; do not take it when the properties of the drug have changed; please use this product under the guidance of a physician; drug interactions may occur if used with other drugs at the same time, please consult a physician or pharmacist for details.
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