What are the precautions for taking tranexamic acid?

The hemostatic mechanism has high affinity with the lysine binding site of plasminogen, which can block the interaction between fibrin and plasminogen containing lysine residues, thereby limiting plasmin activity and achieving hemostasis. Anticoagulant drugs play an anticoagulant effect by binding to one or more sites in the endogenous or exogenous coagulation system to prevent the cascade reaction of the coagulation process. So, what are the precautions for taking tranexamic acid?

What should you pay attention to when taking tranexamic acid?

1. Tranexamic acid should be used with caution in patients with thrombosis tendency (such as acute myocardial infarction) or when massive hematuria occurs due to hemophilia or renal pelvic parenchymal lesions.

2. It is generally believed that it is more appropriate to use this product 8 hours after using the coagulation factors.

3. If necessary, this product should be used on the basis of heparinization.

4. For hypofibrinogenemia bleeding caused by intrauterine stillbirth, heparin treatment is safer than this product.

5. In cases of chronic renal insufficiency, the dosage of this product should be reduced as the drug concentration in urine is often high after administration.

6. When treating bleeding during prostate surgery, the dosage of this product should also be reduced.

Also need to pay attention

Patients should strictly follow the doctor's instructions when using tranexamic acid, and pay attention to the above precautions to ensure the effect of drug treatment. Recently, many patients have listened to bad news on the Internet and increased the dosage of the drug, or reduced the dosage of the drug, which has caused many adverse reactions and even more serious consequences. Therefore, it is strictly forbidden to change the dosage of the drug on your own and should follow the doctor's advice.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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