地拉罗司要如何存放?
How to store it? Deferasirox should be stored at room temperature 25°C (77°F); during excursions a temperature of 15-30°C (59-86°F) is allowed, and deferasirox should be protected from moisture.
The daily dosage of deferasirox dispersible tablets is 20 to 30 mg/kg, and the drug is used once a day. It has good clinical compliance, but it is expensive. In addition to chelating intracellular iron, deferasirox is also related to the prolongation of hepcidin, which can reduce iron absorption in intestinal cells, so the effect of iron removal therapy is better. Deferasirox dispersible tablets should be used with caution in patients with reduced liver and kidney function, elderly patients, pregnant and lactating women, and children under 6 years old; children under 2 years old should not use it.
In 2005, deferasirox (Enrega) was the first oral iron chelator approved by the FDA for routine use and is currently commercially available in more than 80 countries.
Deferasirox (Enrego), which is available in China, is an imported version originally developed by Novartis. Patients can go to major domestic hospitals to buy it through pharmacies, but the price is eye-popping, costing about $24,000 a month. The cost has put it beyond the reach of many working-class families, but the rise of generic drugs has given these families renewed hope. Currently, there are generic and original versions of Deferasirox (Enrega) available in India, but the price is very satisfactory.
The price of Novartis (Enrig) imported from Switzerland to India is about $700, and the specification is 400mg*30 tablets/box. The price of Deferasirox (Enrego) produced by an Indian pharmaceutical factory is about $500, and the specification is 500*30 tablets/box, which is more suitable for long-term use by patients.
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