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Compared with deferoxamine, it is more convenient and has higher patient compliance. EPIC is currently the largest prospective, open, single-group, global multi-center clinical study designed for patients with iron overload. A total of 341 MDS patients were enrolled, and it could reduce serum ferritin by an average of 372 μg/L in 3 months. More importantly, the benefits of iron removal therapy are not only reflected in the reduction of ferritin levels, but can also improve the patient's hematological response, stabilize and reverse the patient's liver fibrosis, improve the heart's ejection fraction, and prevent the occurrence of important cardiac events such as heart failure and arrhythmia. my country's data also supports the above conclusion. The results of a single-arm, multi-center, prospective clinical study enrolling 64 AA patients with transfusion-related iron overload confirmed the effectiveness and safety of deferasirox in reducing patients' ferritin levels.

How long does it take for deferasirox to take effect? Each patient's condition and physical condition are different, so the time it takes for Deferasirox to take effect is also different. Deferasirox (Enrig) ​​is easier to take effect and heal faster in some patients with better physical fitness and milder illness, while patients with poor physical fitness or more severe illness need to use Deferasirox for a longer period of time to be effective.

Common adverse reactions: diarrhea, vomiting, headache, abdominal pain, fever, rash, increased serum creatinine, etc. Other adverse reactions: increased liver enzymes, cough, throat inflammation, urticaria. While taking medicine, patients with thalassemia are often physically weak, so they should live cautiously, adapt to cold temperatures, and pay attention to preventing external infections; engage in more outdoor activities; breathe fresh air; and engage in appropriate physical exercise. For more information about deferasirox, please contact Medical Companion Travel for details.