瑞士诺华的地拉罗司使用方法
It is used for patients with iron accumulation due to long-term blood transfusion (such as those suffering from thalassemia or other rare anemias). It is suitable for children over two years old and adults. It was approved for marketing in my country in 2010. The original drug manufacturer is Novartis of Switzerland, one of the world's three largest pharmaceutical companies.
How to use deferasirox from Novartis Switzerland: Deferasirox is administered orally. The recommended starting daily dose is 20 mg/kg, administered on an empty stomach, once a day, preferably at the same time every day. Completely dissolve the tablets in water, apple juice or orange juice (100-200mL) by stirring until a clear suspension is obtained and then drink it. The remaining medicine must be added with a small amount of water, apple juice or orange juice and mixed well before taking. Not recommended for dissolution in carbonated drinks or milk as it can cause foaming and slow dispersion.
For patients who receive monthly transfusions of more than 14 mL/kg of packed red blood cells (i.e., more than 4 units/month in adults) and who need to reduce excess iron exposure, a starting dose of 30 mg/kg/day may be considered. For patients who receive monthly transfusions of less than 7 mL/kg of packed red blood cells (i.e., less than 2 units/month in adults) and who need to maintain body iron balance, a starting dose of 10 mg/kg/day may be considered. In patients who have responded well to deferoxamine therapy, an initial dose of deferasirox equal to one-half the deferoxamine dose may be considered.
Do not take it with antacids containing aluminum. Dosage (mg/kg) needs to be calculated and rounded to the nearest whole tablet. Do not use if you are allergic to deferasirox or any of its ingredients.
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Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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