美沙拉秦(Salofalk)的副作用如何缓解

Mesalazine is developed and produced by the German company Dr. FalkPharma GmbH.

Mesalazine side effects and relief methods

1. Common side effects

(1) Gastrointestinal reactions: abdominal pain, diarrhea, nausea, bloating, etc. are the most common.

(2), headache.

(3) Skin rash: including skin itching and urticaria.

2. Relief and coping methods

(1) Gastrointestinal discomfort: You can discuss with your doctor whether it can be taken with or after meals to reduce irritation, but please note that this may slightly affect the efficacy of the medicine. Make sure to drink enough fluids. If symptoms persist or worsen, you should inform your doctor promptly.

(2) Headache: Usually relieved with time, keep adequate rest. If the headache is severe or persistent, consult a doctor.

(3) Skin rash: Stop taking the medicine immediately and contact your doctor to determine whether it is a drug allergy.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Serious side effects of Mesalazine that you need to be alert to

1. Allergic reactions

Such as severe rash, skin and mucosal erosion (Stevens-Johnson syndrome), difficulty breathing, and swelling of the face or throat.

2. Kidney problems

Changes in urine output, edema, and abnormal fatigue may indicate nephritis or renal damage.

3. Liver problems

Such as dark urine, jaundice (yellowing of the skin or whites of the eyes), and pain in the right upper quadrant.

4. Lung problems

Unexplained cough, difficulty breathing, and chest pain.

5. Blood system problems

Unexplained fever, sore throat, mouth ulcers, abnormal bleeding or bruises may be a sign of bone marrow suppression.

6. Pancreatitis

Persistent severe pain in the upper abdomen that may radiate to the back.

Mesalazine Precautions and Interactions

1. Regular monitoring

Before and during treatment, it is recommended to regularly check the patient's blood routine, liver function and renal function to monitor potential risks.

2. Special groups

Pregnant women, lactating women, and patients with liver and kidney dysfunction should use it under the strict guidance of a doctor after weighing the pros and cons.

3. Drug interactions

(1) Combination with anticoagulants (such as warfarin) may increase the risk of bleeding.

(2). Combination with immunosuppressants (such as azathioprine) may increase the risk of bone marrow suppression.

(3) Inform your doctor of all medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements.

Mesalazine usage and dosage

1. Standard dose for adults

(1) Acute phase treatment: 1.5-3 grams per day for ulcerative colitis; 3-4.5 grams per day for Crohn's disease.

(2) Maintenance during the remission period: 1.5 grams per day for ulcerative colitis; 1.5-3 grams per day for Crohn's disease.

2. Children’s dose

The dose needs to be calculated based on body weight, please strictly follow the doctor’s instructions.

3. How to take the medicine

(1) Swallow the tablet whole: Do not chew or crush it to avoid damaging the enteric coating that protects the tablet.

(2) Take before meals: It is recommended to take it with enough liquid at least 1 hour before meals to facilitate the absorption of the drug.