昂丹司琼片进入医保了吗？

Ondansetron: It is a carbazole derivative developed by GlaxoSmithKline (later acquired by Novartis). It was first launched in the UK in 1990 under the trade name Zofran. After being approved by the FDA in December 1992, it has been sold in many countries. In 1991, my country has imported preparations for clinical use in domestic anti-tumor hospitals. The trade name is "Shufuning", which is mainly tablets and intravenous injections. Is the film covered by medical insurance?

According to Medical Companion Travel, ondansetron tablets have been included in my country's "National Basic Medical Insurance, Work Injury Insurance and Maternity Insurance Drug Catalog (2020)" and belong to the scope of Class A drugs. Domestic patients can purchase and use the drug with a hospital prescription, and patients with medical insurance can also enjoy the benefits brought by the medical insurance reimbursement policy, significantly reducing medication costs. Due to the high price of the original drug ondansetron, the cost of medication for patients without medical insurance will increase significantly. Patients can also choose the version of ondansetron that is marketed overseas, which is affordable and cost-effective. Patients in need of medicine can contact domestic legal and formal overseas medical service institutions to obtain the medicine.

Chemotherapy and radiotherapy can cause chromaffin cells in the small intestine to release serotonin (5-HT), which can cause vagal afferent nerve excitation through 5-HT3 receptors, leading to the gag reflex. Ondansetron can block the occurrence of this reflex. This effect is 100 times stronger than the traditional antiemetic drug metoclopramide. Excitation of vagal afferents can also cause the release of 5-HT in the posterior rami of the fourth ventricle, which can also trigger vomiting through central mechanisms. Therefore, the mechanism of action of ondansetron in controlling nausea and vomiting caused by cytotoxic chemotherapy drugs and radiotherapy may be due to antagonizing peripheral and central 5-HT3 receptors. The mechanism of action of ondansetron for postoperative nausea and vomiting is unknown. At the same time, ondansetron can also enhance gastric emptying at antiemetic doses and help reduce nausea; it also has anxiolytic and diazepam effects on the central nervous system, which is helpful in inhibiting the excitement of the vomiting center.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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