昂丹司琼片孕妇能吃吗？

Ondansetron is a potent, highly selective 5-HT receptor antagonist. Chemotherapy drugs and radiation therapy can cause the release of 5-HT in the small intestine, which activates the afferent branch of the vagus nerve through 5-HT3 receptors and triggers the gag reflex. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors located in peripheral and central nervous systems.

An open-label, multicenter study examined the efficacy of ondansetron in preventing non-cisplatin-induced vomiting in 193 patients. All patients received ondansetron 8 mg intravenously 20 minutes before chemotherapy and 4 mg ondansetron tablets orally after chemotherapy, twice a day. Results: The effective rate of ondansetron alone in treating acute vomiting caused by chemotherapy was 93.3% (of which the complete remission rate was 86.0%). The effective rates of antiemetics on days 1 to 5 were 93.3%, 94.8%, 96.9%, 99.5% and 99.5% respectively. This suggests that ondansetron alone is more effective in preventing vomiting caused by non-cisplatin and is also effective in delayed vomiting.

After receiving ondansetron tablets, patients must read the instructions carefully to understand the characteristics and contraindications of the drug. Then take the medicine in accordance with the doctor's instructions and do not take the medicine blindly.

So can pregnant women take ondansetron tablets? Liu Jingtao, deputy director of the Pharmacy Department of Peking University Cancer Hospital, said that whether ondansetron is suitable for a certain group of people, first of all, look at the groups for which ondansetron is contraindicated, including patients who are not undergoing chemotherapy, radiotherapy, or surgery, that is, patients who are not indicated. At the same time, for some special groups such as pregnant women and lactating women, it is also recommended that they take ondansetron tablets with caution. Although there is no clear research confirming that ondansetron will cause adverse reactions in pregnant women or lactating women, it is recommended that everyone try not to take this risk. If you are taking this tablet while breastfeeding, please stop breastfeeding. If you are pregnant, try to avoid taking this medicine.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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