枢丹是什么药？

What kind of medicine is Shudan? The chemical name of (ondansetron hydrochloride) is 2,3-dihydro-9-methyl-3-[(2-methylimidazol-1-yl)methyl]-4(1H)-carbazolone hydrochloride dihydrate. It is a powerful and highly selective 5-HT3 receptor antagonist with strong antiemetic effect. Ondansetron hydrochloride exerts antiemetic effects by antagonizing 5-HT receptors on neurons located locally in the peripheral and central nervous system.

Shudan (ondansetron hydrochloride) is approved for: ① nausea and vomiting caused by cytotoxic drug chemotherapy and radiotherapy; ② prevention and treatment of nausea and vomiting after surgery.

For vomiting caused by highly emetic chemotherapy drugs, Shudan (ondansetron hydrochloride): Inject 8 mg of ondansetron hydrochloride injection intravenously 15 minutes before chemotherapy, 4 hours, and 8 hours after chemotherapy, and take 8 mg of ondansetron hydrochloride tablets orally every 8 hours after stopping chemotherapy for 5 days.

Shudan (Ondansetron Hydrochloride) treats vomiting caused by chemotherapy drugs that are not very emetic: Inject 8 mg of Ondansetron Hydrochloride Injection intravenously 15 minutes before chemotherapy, and then take 8 mg Ondansetron Hydrochloride Tablets orally every 8 hours for 5 days.

Shudan (ondansetron hydrochloride) for vomiting caused by radiotherapy: the first dose of 8 mg tablets must be taken 1-2 hours before radiotherapy, and then 8 mg ondansetron hydrochloride tablets should be taken orally every 8 hours. The course of treatment depends on the course of radiotherapy.

Shudan (ondansetron hydrochloride) is used to prevent nausea and vomiting after surgery: 4mg (1 tube) is infused intravenously during anesthesia.

(Ondansetron hydrochloride) For high-dose cisplatin, 20 mg of dexamethasone sodium phosphate can be added intravenously before chemotherapy, which can enhance the effect of ondansetron hydrochloride on vomiting caused by highly emetic chemotherapy.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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