日本的埃索美拉唑治疗胃病可以吗

The active ingredient in (Nexium) magnesium enteric-coated tablets is esomeprazole magnesium. Esomeprazole is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. Today we will learn more about Japan’s esomeprazole. Is it okay to treat gastric problems?

Esomeprazole (Nexium) magnesium enteric-coated tablets are suitable for the treatment of gastroesophageal reflux disease (GERD), erosive reflux esophagitis, and long-term maintenance treatment to prevent recurrence of cured esophagitis patients.

In a clinical comparative study of esomeprazole (Nexium) and omeprazole in the treatment of reflux esophagitis, the total effective rate of esomeprazole was 97.18%, which was significantly higher than 84.51% of omeprazole, and there was no significant difference in the incidence of adverse reactions. Chen Caiming conducted a cost-effectiveness analysis of omeprazole and esomeprazole in the treatment of duodenal ulcer. The recovery rate of the esomeprazole group was 92.6%, which was higher than that of omeprazole, 78.6%. The results proved that esomeprazole has cost and effectiveness advantages.

Esomeprazole (Nexium) reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. The R-isomer and S-isomer of esomeprazole have similar pharmacodynamic properties. Esomeprazole is a weak base, which is concentrated in the high-acid environment of the acid secretion microtubules of parietal cells and converted into an active form, thereby inhibiting the H+/K+-ATPase (proton pump) at this site, inhibiting both basic gastric acid secretion and stimulated gastric acid secretion. Esomeprazole should be taken and discontinued correctly according to the condition and under the guidance of a professional doctor to ensure medication safety.

Esomeprazole (Nexium) has been marketed in many countries. In 2000, the oral formulation of esomeprazole was first launched in Sweden. In 2001, it was approved by the FDA to be marketed in the United States under the trade name esomeprazole. In 2003, esomeprazole sodium for injection developed by AstraZeneca was first launched in Sweden and was approved for marketing in the United States in 2005.

Esomeprazole (Nexium) tablets should be swallowed whole with liquid and should not be chewed or crushed. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive reflux esophagitis. 40 mg once daily for four weeks. For patients whose esophagitis has not been cured or who have persistent symptoms, it is recommended to take medication for another four weeks. - Long-term maintenance esomeprazole treatment for patients with cured esophagitis to prevent recurrence. 20 mg once daily. To control the symptoms of gastroesophageal reflux disease (GERD), patients without esophagitis should take 20 mg once a day. If the symptoms are not controlled after 4 weeks of medication, the patient should undergo further examination. Once the symptoms are eliminated, immediate treatment can be used for subsequent symptom control, that is, 20 mg orally once a day when necessary.

The above is the content of (Nexium) effect, I hope it can help you!

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