贝罗司他胶囊怎么使用？副作用是什么？

Hereditary angioedema (HAE) is an autosomal dominant genetic disease. Its onset is caused by the lack or dysfunction of C1 esterase inhibitor (C1-INH) in serum and tissues. The incidence rate reported abroad is approximately 1/50,000. The clinical manifestations of the disease are complex and diverse. Most patients begin to develop symptoms before the age of 10. The main manifestations are episodic body surface and visceral mucosal edema, which usually subsides in 2 to 3 days. Although this disease is rare, it has attracted attention because the incidence of laryngeal edema is high (30%) and is often life-threatening. Capsule (berotralstat) is the first oral non-steroidal plasma kallikrein (KLKB1) inhibitor developed by Biocryst. The drug was approved by the FDA on December 3, 2020. This product is a capsule, used for the prevention of hereditary angioedema (HAE) attacks in adults and pediatric patients 12 years and older.

How to use Berostat capsules? What are the side effects?

: Gastrointestinal reactions, back pain, rash, abdominal pain, vomiting, diarrhea, gastroesophageal reflux, abnormal liver function indicators, etc.

Finally, the editor of Medical Companion Travel would like to remind patients who are currently using berosstat capsules that there has been a lot of loose news recently saying that if patients feel that the effect of the drug is not good, they can increase the dose of the drug, or that if the side effects are too great during the medication, the dose of the drug can be reduced. These are not scientifically based. Only by following the doctor's instructions can the effect of the drug itself be maximized.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.