阿布西替尼哪里买的到？

Absitinib, also known as Xibetan, has been launched in China and can be purchased in China. The common purchase channels include regular pharmacies, hospital pharmacies, outpatient pharmacies, online pharmacies, overseas purchases, medical service institutions, consulting patients, adding patient groups, etc. You can choose according to your actual situation.

Marketing information

On January 14, 2022, the U.S. FDA approved the marketing of abuxitinib for the treatment of adult patients with relapsed moderate to severe atopic dermatitis who are not suitable for the use of existing systemic therapies, or these therapies cannot control the disease.

On April 11, 2022, the State Food and Drug Administration of China announced that Abxitinib tablets were approved for marketing in China. It is suitable for adult patients with refractory, moderate to severe atopic dermatitis who have responded poorly to other systemic treatments (such as hormones or biological agents) or are not suitable for the above treatments.

Where to buy Absitinib

If you need to buy it, here are some reference ways to purchase the drug:

1. Regular pharmacies: You can go to legal pharmacies in your area to buy Absitinib, and you can ask the pharmacist if he sells Absitinib.

2. Hospital pharmacy: If you are receiving hospital treatment, you can buy Absitinib in the hospital pharmacy. You need a doctor's prescription before you can buy it.

3. Outpatient pharmacy: You can go directly to the hospital outpatient clinic for treatment or review, and the outpatient doctor will issue a prescription and purchase it in the outpatient pharmacy.

4. Online pharmacies: Some authorized online pharmacies may also sell Absitinib, which also requires a doctor’s prescription to purchase. It is recommended to choose a legal and formal online pharmacy.

5. Purchase abroad: You can go to the United States, Japan, the United Kingdom and other countries for overseas medical treatment. You can buy Absitinib directly, or you can buy Absitinib directly in foreign pharmacies.

6. Medical service institutions: There are some medical service institutions in China that will cooperate with pharmaceutical manufacturers in various countries to provide sales services of Absitinib, and the drug version is relatively complete. You can usually buy Absitinib. You can consult their customer service staff in advance to know whether you can buy Absitinib and what the price is.

7. Consult patients: You can consult lung cancer patients you know around you or online, and ask them where they bought Absitinib, and you can also ask them to help buy it.

8. Add a patient group: You can add a reliable lung cancer patient group online, and ask members in the group whether they have purchased abusitinib, how to purchase it, price reference, etc.

The price of Absitinib

Currently, we know that the specification of Absitinib is 100mg*14 tablets, and the reference price is approximately between 1100$-3150$. The specific price needs to be based on the actual price.

Efficacy of Absitinib in the Treatment of Atopic Dermatitis

In a phase 3 double-blind trial, patients with atopic dermatitis who were unresponsive to topical drugs or required systemic therapy were randomly assigned to receive 200 mg or 100 mg of abusitinib once daily, 300 mg of dupilumab subcutaneously every other week (after a 600 mg loading dose), or placebo.

A total of 838 patients underwent randomization; 226 patients were assigned to the 200 mg abositinib group, 238 to the 100 mg abositinib group, 243 to the dupilumab group, and 131 to the placebo group.

IGA responses observed at Week 12 were 48.4% in the 200 mg abositinib group, 36.6% in the 100 mg abusitinib group, 36.5% in the dupilumab group, and 14% in the placebo group.

The EASI-75 responses observed at week 12 were 70.3%, 58.7%, 58.1%, and 27.1% respectively. In terms of pruritus response at week 2, the 200 mg dose of abusitinib was superior to the 100 mg dose.

Absitinib at a once-daily dose of 200 mg or 100 mg significantly reduced signs and symptoms of moderate to severe atopic dermatitis at weeks 12 and 16.

Summary

Consult a doctor or dermatologist before using Absitinib to ensure that Absitinib is suitable for your condition and to understand how to use it correctly. In addition, it is important to understand the potential side effects and precautions of the medication. If you need to get or take abisitinib, you can talk to your doctor or medical professional for further help.

References:

Bieber T, Simpson EL, Silverberg JI, Thaçi D, Paul C, Pink AE, Kataoka Y, Chu CY, DiBonaventura M, Rojo R, Antinew J, Ionita I, Sinclair R, Forman S, Zdybski J, Biswas P, Malhotra B, Zhang F, Valdez H; JADE COMPARE Investigators. Abrocitinib versus Placebo or Dupilumab for Atopic Dermatitis. N Engl J Med. 2021 Mar 25;384(12):1101-1112. doi: 10.1056/NEJMoa2019380. PMID: 33761207.

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