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What is collagenase ointment? How to use collagenase ointment?

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

It can be used to treat burns and scald wounds and promote their healing. It is the only hydrolytic enzyme that can break down your own collagen. Collagenase can decompose necrotic tissue in the wound and promote the formation of granulation tissue and epithelial tissue in the wound. Collagenase has the function of hydrolyzing natural collagen under physiological pH environment, and has the unique function of digesting natural and denatured collagen in necrotic tissue.

Collagenase can degrade collagen fibers at the edge of the wound and has a good debridement effect, thereby promoting granulation growth, epithelialization, and accelerating wound healing. Fifty cases of deep second-degree burn wounds were selected and randomly divided into collagenase ointment treatment group and control group. The wounds in the control group were treated with Vaseline ointment. The test results showed that the necrotic tissue clearance rate of the wounds in the collagenase ointment treatment group was significantly greater than that of the wounds in the control group, and the healing time was also shorter than that in the control group. Therefore, it can be concluded that collagenase ointment can effectively remove necrotic tissue from deep second-degree burn wounds and accelerate wound healing. Collagenase ointment has a significant therapeutic effect and has a positive effect on the patient's condition.

How to use collagenase ointment?

Before using collagenase ointment, the wound should be gently wiped with a saline-soaked gauze pad or the required cleanser compatible with collagenase ointment to remove debris and digestion, and then rinsed with saline solution. Collagenase ointment can be applied directly to the wound, or it can be applied to a sterile gauze pad, which is then bandaged over the wound and secured properly. When debridement of necrotic tissue is complete and granulation tissue is well established, use of collagenase ointment should be discontinued. People with local or systemic allergies to the ingredients contained in collagenase ointment should not use this drug for treatment.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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