日本维利西呱价格多少？

How much does Viricigua cost in Japan?

Vericiguat, a soluble guanylate cyclase (sGC) agonist, is the first drug to be used to treat patients with worsening chronic heart failure. It was jointly developed and promoted by Bayer and Merck. It was approved by the US FDA for marketing in 2021. It is used to reduce the risk of cardiovascular death and heart failure (HF) hospitalization due to heart failure hospitalization or the need for treatment. As an outpatient intravenous diuretic, the injection rate is less than 45% in adults with symptomatic chronic heart failure.

It is understood that direct mail from Japan in overseas markets is roughly:

Specification 2.5mg*100 tablets price is about 2300$;

Specification 5mg*100 tablets price is about 4500$;

Specification 10mg*100 tablets price is about 7500$.

How much does Viricigua cost in Japan per month?

The recommended starting dose of veliciguat is 2.5 mg taken orally daily with food. The dose of veliciguat should be doubled approximately every 2 weeks to achieve the patient's target maintenance dose of 10 mg per day. According to the usage and dosage of vericiguat, it is 2.5 mg per day in the first week, 2 weeks later, that is, 5 mg per day in the third to fourth weeks, and starting from the fifth week, the maintenance dose is 10 mg per day. In other words, in the first month, you need 14 tablets + 28 tablets = 42 tablets of Vericiguat. You only need one box of Vericiguat with a specification of 2.5mg*100 tablets and the price is about $2,300.

However, due to different specific conditions of patients, the usage and dosage will be different. The specific dosage of Vericiguat should be taken according to the doctor's instructions and cannot be changed at will. Patients who need the Japanese version can go abroad to buy it in Japan, but the cost will be higher and the purchase of medicine is not guaranteed. Patients who are inconvenient to go abroad can obtain it through domestic professional overseas medical service institutions. Drugs can be sent directly to their homes from Japan, so they can obtain overseas drugs without leaving home. Moreover, patients can obtain overseas drugs more securely by signing a drug subscription contract. For more details, please consult customer service personnel.

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