维利西呱能治好心衰吗

Introduction: Vericiguat is a drug used to treat chronic heart failure. It helps improve heart function through its unique mechanism of action. This article will discuss in detail whether Vericiguat can cure heart failure, how to take it correctly, and contraindications to help patients better understand this drug.

Can Vericiguat cure heart failure

It is a drug for chronic heart failure. Its mechanism of action is mainly by activating guanylyl cyclase and increasing intracellular cyclic guanosine monophosphate (cGMP) levels, thereby relaxing vascular smooth muscles and reducing cardiac load.

Improve heart function

Veliciguat helps improve the heart's pumping function by reducing the load on the heart. In patients with chronic heart failure, this effect can significantly relieve symptoms such as dyspnea and fatigue.

Prolong survival

Clinical studies have shown that veliciguat can prolong the survival of patients with chronic heart failure, which is of great significance for improving patients' quality of life and long-term prognosis.

Relieving symptoms

Veliciguat can effectively relieve symptoms in patients with chronic heart failure, such as edema and reduced mobility. Patients often experience significant reduction in symptoms after use.

Although veliciguat cannot completely cure heart failure, it can significantly improve heart function, prolong survival and relieve symptoms. It is one of the important drugs for the treatment of chronic heart failure.

How to take Vericiguat

Correct use of Vericiguat is the key to ensuring its efficacy. Patients need to follow the doctor's instructions and use it strictly in accordance with the prescribed dosage and usage.

Initial dose

The initial dose of vericiguat is usually 2.5 mg once a day, and the doctor will gradually adjust the dose according to the patient's condition and tolerance.

Dose adjustment

During treatment, the doctor may adjust the dose based on the patient's response. The maximum recommended dose is 10 mg once daily, and patients are not allowed to adjust the dose themselves.

Dosing time

Veliciguat should be taken at a fixed time every day, preferably in the morning. This can maintain a stable concentration of the drug in the body and improve the efficacy.

By following the correct dosage regimen, patients can maximize the therapeutic effects of Veliciaguat while reducing the occurrence of side effects.

Contraindications of Vericiguat

Although Vericiguat has significant effects on chronic heart failure, not all patients are suitable for its use. Understanding its contraindications is crucial for safe use of the drug.

Allergic Reaction

This drug is contraindicated in patients who are allergic to veliciaguat or its components. An allergic reaction may manifest as a rash, difficulty breathing, or facial swelling and requires immediate discontinuation of medication and medical attention.

Severe hepatic and renal insufficiency

Patients with severe hepatic and renal insufficiency should avoid using vericiguat. Since the drug is mainly metabolized by the liver and kidneys, hepatic and renal insufficiency may increase the risk of drug accumulation.

Hypotension

Veliciguat may cause hypotension, so patients with severe hypotension should use it with caution. Blood pressure changes need to be closely monitored during treatment.