哪种人不适合吃阿托伐他汀？阿托伐他汀有哪些副作用？

One of the most commonly used lipid-lowering drugs in the clinical treatment of cardiovascular and cerebrovascular diseases is HMG-coA reductase inhibitor. Atorvastatin reduces cholesterol by inhibiting the synthesis of cholesterol. It is often used clinically for patients with primary hypercholesterolemia and mixed hyperlipidemia. It can also be used for coronary heart disease and coronary heart disease-related risks such as diabetes, peripheral atherosclerosis, cerebral infarction and other complications. In addition to its lipid-lowering effect, it also has pleiotropic effects such as anti-inflammatory, antioxidant, improving endothelial function, and anti-atherosclerosis. The combination of atorvastatin and aspirin can effectively treat atherosclerosis, reduce the incidence of cardiovascular and cerebrovascular events, and thus improve the clinical prognosis of patients.

Who is not suitable for taking atorvastatin?

1. It is forbidden for those who are allergic to any ingredients contained in this product.

2. Patients with high blood pressure, heart disease, and stomach problems should use with caution.

3. This product is contraindicated in patients with active liver disease, those whose serum aminotransferase continues to rise more than three times the normal upper limit for unknown reasons, those with myopathy, those who are pregnant, lactating, and any women of childbearing age who have not taken appropriate contraceptive measures.

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1. Liver function damage is mainly clinically manifested as an increase in aspartate and alanine aminotransferase. If the elevation of transaminases is > three times the upper limit of normal, the drug should be discontinued or the dose should be reduced clinically, and hepatoprotective treatment should be performed;

2. Muscle injury, patients may present with muscle weakness and myalgia, with or without elevated muscle enzymes. If muscle enzymes exceed five times the normal value, the drug must be stopped immediately;

3. Some patients will also experience muscle weakness and myalgia, but there will be no increase in creatine kinase. If these patients cannot tolerate it, they need to stop taking the drug or switch to other statin drugs that cause less muscle damage.

Generally speaking, the safety of atorvastatin is very high, the proportion of clinical side effects is relatively small, no more than 3%, and the clinical benefits far outweigh its possible risks.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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