依普利酮医保报销多少呢？

Essential hypertension is often accompanied by activation of the renin-angiotensin-aldosterone system (RASS) and secondary hyperaldosteronemia. Therefore, aldosterone receptor antagonists are an important class of drugs for the treatment of essential hypertension. As the first selective aldosterone receptor antagonist, it has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypertension. The "China Hypertension Prevention and Treatment Guidelines 2010" also proposed eplerenone as one of the main antihypertensive drugs.

The EPHESUS trial showed that for patients with left ventricular ejection fraction (LVEF) <40% and heart failure within 3 to 14 days after myocardial infarction, the addition of eplerenone to standard treatment can reduce all-cause death by 15%, primary combined endpoint events (cardiovascular death or hospitalization for cardiovascular events) by 17%, and sudden cardiac death (sudden cardiac death) by 21%. cardiac death, SCD).

The combination of eplerenone and enalapril can significantly reduce left ventricular weight, and the addition of hydrochlorothiazide and amlodipine can further reduce it. Previous studies have confirmed that left ventricular mass index is associated with event-free survival. In studies on patients with diabetes mellitus and proteinuria, both eplerenone and enalapril can reduce systolic blood pressure and diastolic blood pressure, but eplerenone reduces the urinary albumin/inosine ratio UACR more significantly than enalapril.

It is understood that eplerenone is not currently on the market in my country, so there is no issue of medical insurance reimbursement. Even if it is sold in Hong Kong and Taiwan, mainland residents cannot use medical insurance.

Generic drugs produced in India are widely popular among Chinese patients. Since there are no high research and development costs, India's Lupine Pharmaceuticals' eplerenone, 50mg*100 tablets, is priced at about RMB 500, which will not cause excessive financial burden to patients and is a very suitable choice.