依普利酮治疗高血压的效果如何呢？

(Eplerenone, Inspra) is a selective aldosterone receptor antagonist. There are tablets on the market, eplerenone tablets (25mg, 50mg). A drug primarily used to treat heart failure and improve prognosis. Indications are 1. Congestive heart failure after acute myocardial infarction: Eplerenone can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%). Clinical trials have proven that this product can also be used for congestive heart failure after acute myocardial infarction; 2. Anti-hypertension: Eplerenone can be used alone or in combination with other antihypertensive drugs for the treatment of hypertension.

How effective is eplerenone in treating hypertension?

Clinical trials evaluate the clinical efficacy and safety of eplerenone (Inspra) and losartan in the treatment of essential hypertension. Methods 80 patients were selected and randomly divided into eplerenone group and losartan group, 40 cases in each group. Eplerenone tablets 50 mg and Losartan potassium tablets 50 mg were administered orally once/d for 12 weeks. Before and after treatment, a number of biochemical indicators, 24-hour ambulatory blood pressure, and adverse reactions were mainly detected.

Results Compared with before treatment, the blood pressure of the two groups dropped significantly, and the differences were statistically significant (P0.05); comparing the two groups, there was no statistically significant difference in the blood pressure reduction between eplerenone and losartan (P0.05). Comparing the biochemical indicators between the two groups, the difference was not statistically significant (P0.05).

The conclusion shows that (Eplerenone, Inspra) is a good medicine for the treatment of hypertension. It has a protective effect on the liver, heart, and kidneys without damaging the organs. This medicine can promote urination without losing potassium. Eplerenone and losartan. 1 time/d. Taking 50 mg can effectively control blood pressure in patients with mild and moderate hypertension. Good safety and compliance.