一盒依普利酮多少钱？

It is a new type of selective aldosterone receptor antagonist. It was approved for clinical use by the State Food and Drug Administration in 2002. The pure product is white or off-white crystal. It has stronger aldosterone antagonism than spironolactone and has extremely low affinity for androgen and progesterone receptors. It has few adverse reactions. It has definite efficacy in the treatment of hypertension, heart failure and myocardial infarction. It has fewer adverse reactions and good tolerance. It is a good alternative drug to spironolactone.

For severe hypertension that cannot be controlled by a combination of multiple antihypertensive drugs, the addition of eplerenone can significantly reduce blood pressure, especially the decrease in systolic blood pressure is more significant. Combined treatment with angiotensin-converting enzyme inhibitors (ACEI) and beta-blockers can improve patients' quality of life and reduce mortality in severe heart failure and myocardial infarction.

The combined use of standard treatment drugs for the treatment of heart failure after acute myocardial infarction can reduce the total mortality rate in the treatment group by 15% (P=0.008); eplerenone and enalapril are equally effective in reversing left ventricular hypertrophy and hypertension, with fewer cough side effects, and the combined effect is more obvious; there are few adverse reactions, except for the adverse reactions of increased blood potassium, other adverse reactions are no different from the placebo group; there are almost no sex hormone-related side effects of spironolactone.

The FDA (U.S. Food and Drug Administration) has approved eplerenone for use in stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and congestive heart failure after acute myocardial infarction (MI) to improve survival rates. Eplerenone is the first aldosterone receptor blocker approved for this indication. The FDA's approval was based on the results of the EPHESUS (Eplerenone Efficacy and Survival Study in Heart Failure After Acute Myocardial Infarction) trial. In patients with heart failure after myocardial infarction, eplerenone plus standard care reduced mortality by 15% compared with placebo and standard care (ACE inhibitors and beta-blockers).

How much does a box of eplerenone cost? 

According to Medical Companion Travel, we learned that eplerenone 50mg✘100 tablets from India's Lupine Pharmaceuticals is about $500. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices.