依普利酮在国内有卖吗？

Eplerenone (Planep) can be used for congestive heart failure after acute myocardial infarction. Eplerenone can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%). Clinical trials have proven that eplerenone (Planep) can also be used for post-acute myocardial infarction heart failure and acute myocardial infarction. After death of congestive heart failure, the commonly used domestic aldosterone receptor antagonist spironolactone has a significant protective effect on the cardiovascular system, but its sex hormone-related side effects limit its application. As a new generation of selective aldosterone receptor antagonist, eplerenone (Planep) provides a new method for the treatment of cardiovascular diseases.

Studies have shown that eplerenone (Planep) can cause a sustained increase in plasma renin and serum aldosterone, and at the same time block the feedback regulatory effect of aldosterone. However, the increase in plasma renin activity and the increase in aldosterone levels in the systemic circulation will not offset the blood pressure control effect of eplerenone (Planep). Eplerenone and spironolactone work on the same principle. Long-term use of spironolactone can cause endocrine disorders, while eplerenone has good tolerance and has the advantage of less side effects, avoiding the side effects of endocrine disorders.

Is eplerenone available in China?

At present, eplerenone (Planep) has not been launched in China, so eplerenone (Planep) is not sold in China. If domestic patients need eplerenone (Planep), they can choose eplerenone (Planep) listed in India. The Indian version of eplerenone (Planep) is produced by Lupine Pharmaceuticals of India, and the specification is 50mg✘100 tablets. The price is about $500. If patients want to buy the Indian version of Eplerenone (Planep), they can go abroad for medical treatment and buy the medicine with a prescription, or they can contact domestic overseas medical service agencies (such as Medical Companion Travel) to purchase Eplerenone (Planep) through direct mail.