依普利酮国内有售吗

Currently, it is only available in the United States and Japan. China has not yet been approved for marketing. Patients who want to purchase this drug must go abroad to purchase it themselves, or find domestic and overseas medical institutions to purchase it. It is understood that the price of the original drug of eplerenone in the United States is relatively high. The specifications are 50mg-30 tablets/box, and the price is about 124.09 US dollars. The price is very expensive, but fortunately, India also has a generic version of this product, which has the same efficacy and is affordable. According to Medical Travel, we learned that the price of eplerenone 50mg 100 tablets from India's Lupine Pharmaceuticals is about $500. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices.

Eplerenone is a selective aldosterone receptor antagonist that only acts on mineralocorticoid receptors but not on androgen and progesterone receptors. Eplerenone treats patients with stage 1 and stage 2 hypertension with similar efficacy rates and reductions in systolic and diastolic blood pressure as enalapril. Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels for whom angiotensin-converting enzyme inhibitors and angiotensin II receptor inhibitors are not effective. It also has a good antihypertensive effect on simple systolic hypertension, and has a good antihypertensive effect on diet-induced obesity-related hypertension. In addition, eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.

Do not combine with potassium supplements, potassium-containing salts or contraindicated drugs (potassium-sparing diuretics, strong inhibitors of CYP450 liver enzymes). Non-steroidal anti-inflammatory drugs and lithium can affect the blood concentration of this product and affect its efficacy. Patients with high serum potassium, type 2 diabetes patients with microalbuminuria, patients with high serum creatinine levels, and patients with muscle clearance <50 mL/min should not take this product. Pregnant women, children, and those with hepatic insufficiency, chronic cardiac insufficiency, and renal insufficiency should use with caution.