依普利酮（Planep）在中国上市了吗？

It is a new type of selective aldosterone receptor antagonist that was approved for clinical use by the my country Food and Drug Administration in 2002.

Eplerenone has a stronger antagonizing effect on aldosterone than spironolactone, and has extremely low sensitivity to androgens and luteal copper protein kinase. It has few side effects and is effective in treating hypertension, heart failure and myocardial infarction. It has fewer side effects and good tolerance. It is an excellent substitute for spironolactone. Is eplerenone (Planep) on the market in China?

It is understood that eplerenone is not currently approved for marketing in my country, so patients can only purchase the version marketed abroad.

The price of the original drug of eplerenone is relatively high. The original drug of eplerenone in the United States is available in two specifications, 25mg, 30 tablets/box, priced at about 118.71/USD; 50mg, 30 tablets/box, priced at about 124.09/USD. This price is not something that ordinary patients can afford in the long term! 

At present, the Indian version of eplerenone is widely used on the market. The price of eplerenone in India: the specification is 50mg*100 tablets, and the price is around $400. Due to exchange rate fluctuations and different prices, please contact Medical Companion Travel for specific prices!

Eplerenone combined with angiotensin-converting enzyme inhibitors (ACEI) and beta-blockers can improve quality of life and reduce mortality. Its advantages include:

(1) For the treatment of heart failure after acute myocardial infarction, combined with standard treatment drugs can reduce the total mortality in the treatment group by 15% (P=0.008);

(2) Eplerenone and enalapril are equally effective in reversing left ventricular hypertrophy and hypertension, with fewer cough side effects, and the combined effect is more obvious;

(3) There are few adverse reactions. Except for the adverse reactions of increased blood potassium, other adverse reactions are no different from the placebo group;

(4) There are almost no sex hormone-related side effects of spironolactone.

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