依普利酮降血压效果明显吗?
Is the blood pressure lowering effect obvious?
Eplerenone is effective in treating patients with stage 1 and stage 2 hypertension and has similar effectiveness and magnitude in reducing systolic and diastolic blood pressure as enalapril. Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels who do not respond well to angiotensin-converting enzyme inhibitors and angiotensin receptor inhibitors.
Eplerenone (Planep) also has a good antihypertensive effect on simple systolic hypertension, and has a good antihypertensive effect on diet-induced obesity-related hypertension. In addition, eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.
Patients should pay attention to the following when using eplerenone for treatment:
Patients who are allergic to any of the components of eplerenone should not be treated with this medicine.
Hyperkalemia may occur with the use of eplerenone, the risk of which is increased in patients with proteinuria, diabetes mellitus, renal impairment, and in patients concurrently taking angiotensin II inhibitors, angiotensin-converting enzyme (ACE) inhibitors, nonsteroidal anti-inflammatory drugs, or moderate CYP3A inhibitors. Patients need to be closely monitored during treatment.
Treatment with eplerenone (Planep) should be used with caution in patients with diabetes and post-myocardial infarction heart failure (especially those with proteinuria), as this may increase the risk of hyperkalemia.
The above is the introduction about (eplerenone), I hope it can help everyone. If patients have other questions about the drug (such as drug price, purchasing channels, etc.), they can consult the medical companion travel service.
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