依普利酮功效与禁忌

The efficacy of eplerenone of India's Lupine Pharmaceuticals: It is a selective aldosterone receptor antagonist, which only acts on mineralocorticoid receptors and does not act on androgen and progesterone receptors. Eplerenone has a potassium-sparing diuretic effect, can reverse left ventricular hypertrophy, lower blood pressure, and treat primary aldosteronism. Compared with spironolactone, eplerenone can prevent gynecomastia and sexual dysfunction, has a better potassium-sparing diuretic effect, and is mainly used clinically to treat hypertension and heart failure. This drug reaches its peak blood concentration 1.5 hours after taking it, has a half-life of about 4 to 6 hours, and its absorption is not affected by food.

Contraindications of eplerenone from Lupine Pharmaceuticals India: (1) It is contraindicated in patients allergic to eplerenone. (2) Patients with excessive serum potassium, type 2 diabetes patients with microalbuminuria, patients with excessive serum creatinine levels, and patients with muscle intoxication clearance <50 mL/min should not take eplerenone. (3) Pregnant women, children, and those with hepatic and renal insufficiency should use with caution. (4) Eplerenone cannot be combined with potassium supplements, potassium-containing salts or contraindicated drugs (potassium-sparing diuretics, strong inhibitors of CYP450 liver enzymes). Non-steroidal anti-inflammatory drugs and lithium can affect the blood concentration of this product and affect its efficacy. (5) Use with caution in patients with diabetes and heart failure after myocardial infarction (especially those with proteinuria); the risk of hyperkalemia is increased.

The above are the relevant matters related to the efficacy of Indian Lupine Pharmaceuticals and the contraindications of Indian Lupine Pharmaceuticals eplerenone compiled by the editor of Medical Companion Travel. Patients need to read the instructions of Indian Lupine Pharmaceuticals eplerenone carefully before taking the medicine. To learn more about eplerenone from Lupine Pharmaceuticals in India, please consult the Medical Companion Travel Service.

Recommended hot articles: /newsDetail/86612.html