依普利酮的价格

What is the price of Lupine Pharmaceuticals in India? Medical Companion Travel has learned that a box of eplerenone (Planep) produced by Lupine Pharmaceuticals in India costs about $500. For detailed price information, please consult the Medical Companion Travel Service for detailed information.

The indications of Planep are: 1. Congestive heart failure after acute myocardial infarction: Eplerenone can improve the quality of life of patients with left ventricular dysfunction (ejection fraction ≤ 40%). Clinical trials have proven that this product can also be used for congestive heart failure after acute myocardial infarction; 2. Anti-hypertension: Eplerenone can be used alone or in combination with other antihypertensive drugs for the treatment of hypertension.

A clinical trial was conducted to explore the effects of Planep and losartan on arterial stiffness and central arterial pressure (CAP) in patients with dual-stage mild to moderate essential hypertension with elevated systolic and diastolic blood pressure. The trial included 84 patients with mild to moderate essential hypertension [diastolic blood pressure 90-110mm Hg (1mm Hg=0.133kPa) and systolic blood pressure 140-180mm Hg] were divided into eplerenone group and losartan group, with 42 patients in each group. After taking placebo for 2 weeks, they entered the 12-week trial period. They were given eplerenone (Planep) 50 mg or losartan 50 mg orally once/d, followed by a follow-up visit once/2 weeks. After 4 weeks, if the diastolic blood pressure is ≥90 mm Hg, they will be changed to eplerenone 100 mg orally divided into 2 times or Losartan 100 mg orally once/d. Compared with before treatment, patients in the eplerenone group and losartan group had significantly lower seated systolic and diastolic blood pressures, ambulatory blood pressure parameters, baPWV and CAP.

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