依普利酮效果怎么样？

Hypertension is the most common chronic disease and the main risk factor for cardiovascular and cerebrovascular diseases. Hypertension refers to an increase in systemic arterial blood pressure (systolic blood pressure and/or diastolic blood pressure) as the main feature (systolic blood pressure ≥140 mm Hg mm Hg, diastolic blood pressure ≥90 mm Hg mm Hg). (INSPRA), approved in the United States in 2002, has definite efficacy in the treatment of hypertension, heart failure and myocardial infarction, has fewer adverse reactions and is well tolerated.

Eplerenone has a protective effect on the liver, heart disease, and kidneys without damaging the organs. This drug can promote urination without losing potassium. It also has a good antihypertensive effect on simple systolic hypertension and has a good antihypertensive effect on diet-induced obesity-related hypertension.

The trial is to observe the clinical efficacy of eplerenone in the treatment of mild to moderate essential hypertension. Methods 45 patients with mild to moderate hypertension were randomly divided into Losartan group (22 cases) and Eplerenone group (23 cases). The losartan group and the eplerenone group used a double-blind, double-simulation, positive drug parallel control method, and received losartan and eplerenone treatment respectively. After 4 weeks of treatment, if the blood pressure did not reach the target, the drug dose was doubled and the treatment was continued for 4 weeks; if the blood pressure reached the target, the original dose was maintained and the treatment was continued for 4 weeks. Results After 8 weeks of treatment, compared with before treatment, the average sitting diastolic blood pressure of the losartan group decreased by (11.33±1.09) mmHg, and the average sitting diastolic blood pressure of the eplerenone group decreased by (13.02±1.40) mmHg. There was no statistical significance between the two groups (P is 0.05). The conclusion shows that both eplerenone and losartan can effectively reduce the average sitting systolic blood pressure and diastolic blood pressure in patients with hypertension.

How effective is India's Lupine Pharmaceuticals eplerenone?

The effect of India's Lupine Pharmaceuticals is consistent with that of the original drug and can significantly reduce high blood pressure.

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