依普利酮可用于治疗什么病症？

It is a new generation of selective aldosterone antagonist. Eplerenone has a protective effect on the liver, heart disease, and kidneys without damaging the organs. It can promote urination without losing potassium. It also has a good antihypertensive effect on simple systolic hypertension. Today let’s take a detailed look at what diseases eplerenone produced by India’s Lupine Pharmaceuticals can be used to treat?

Lupine Limited is an Indian multinational pharmaceutical company. Eplerenone has not yet been launched in China, and there is no medical insurance. Eplerenone indications: 1. Used for congestive heart failure after acute myocardial infarction. 2. Used to treat high blood pressure.

Eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for patients with hypertension and diabetes.

The dosage of eplerenone varies for different patients: 1. Congestive heart failure after acute myocardial infarction: The recommended dose is 50 mg/time, once/day. The initial dose should be 25 mg/time, once/day, and within 4 weeks, the dose should be gradually increased to 50 mg/time, once/day under the conditions tolerated by the patient within 4 weeks.

2. Anti-hypertensive: Eplerenone can be used alone or in combination with other anti-hypertensive drugs. The recommended initial dose for use alone is 50mg/time, once/day. Obvious pressure-reducing effect will appear within four weeks of taking the medicine. If the pressure effect is not obvious, it can be increased to 50mg/time, 2 times/day. Higher dosages are not recommended, otherwise there is an increased risk of adverse reactions such as hyperkalemia.

Eplerenone also has a good antihypertensive effect in patients with essential hypertension with low renin levels who have poor effects on angiotensin-converting enzyme inhibitors and angiotensin II receptor inhibitors. It also has a good antihypertensive effect on simple systolic hypertension.

It is a selective aldosterone receptor antagonist, which only acts on mineralocorticoid receptors and does not act on androgen and progesterone receptors, and has fewer side effects.