依普利酮服用方法

It is the first selective aldosterone receptor antagonist and has been used to treat hypertension and left ventricular dysfunction after acute myocardial infarction. It can effectively lower blood pressure, improve cardiac function and reduce myocardial damage. Today let’s take a look at how to take eplerenone from Lupine Pharmaceuticals in India.

Common doses of eplerenone for the treatment of congestive heart failure in adults:

1. Initial dose: 25 mg orally, once a day; and gradually increase to the target dose within 4 weeks as tolerated by the patient.

2. Target dose: 50 mg, orally, once a day.

Common doses of eplerenone for the treatment of hypertension in adults:

Eplerenone can be used alone or in combination with other antihypertensive drugs. Initial dose: 50 mg, orally, once a day; Maintenance dose: 50 mg, orally, 1-2 times a day; Maximum dose: 100 mg/day; Obvious antihypertensive effect appears within four weeks of medication. Patients whose blood pressure responds inadequately to the initial dose may be increased to 50 mg twice daily.

Lupine Limited is an Indian multinational pharmaceutical company. Eplerenone has not yet been launched in the country, and there is no talk of medical insurance.

The advantages of eplerenone include: 1. For the treatment of heart failure after acute myocardial infarction, combined use with standard treatment drugs can reduce the total mortality rate in the treatment group by 15%; 2. Eplerenone is as effective as enalapril in reversing left ventricular hypertrophy and hypertension, has fewer coughing side effects, and the combined effect is more obvious;

3. There are few adverse reactions. Except for the adverse reactions of elevated blood potassium, other adverse reactions are no different from the placebo group. 4. There are almost no sex hormone-related side effects of spironolactone.

Without damaging the organs, it has a protective effect on the liver, heart disease, and kidneys. It can promote urination without losing potassium. It also has a good antihypertensive effect on simple systolic hypertension and has a good antihypertensive effect on obesity-related hypertension caused by diet. In addition, eplerenone can significantly reduce the ultrafiltration effect of glomeruli and reduce albuminuria in patients with hypertension. This renal protective effect is more obvious for hypertensive patients with diabetes.