曾被国外杂志列入“黑名单”得非那雄胺，还能安全使用吗？非那雄胺的疗效和安全性。

Finasteride is a 4-azasteroid compound that is a specific inhibitor of type II 5a-reductase, an intracellular enzyme that metabolizes testosterone to the more potent form of dihydrotestosterone. It is a 4-azasteroid compound that is a specific inhibitor of type II 5a-reductase, an intracellular enzyme that metabolizes testosterone into the stronger dihydrotestosterone. Today we will learn about finasteride, which has been "blacklisted" by foreign magazines. Is it still safe to use? Efficacy and safety of finasteride.

Experts say: 1 mg of finasteride is currently one of the safe and effective drugs for the treatment of male androgenic alopecia, and it is also the drug of choice. The hair loss treated mainly refers to male androgenic alopecia. Usually the course of medication is 3 months. Generally, after 3 months of medication, hair loss will be controlled and the process of shedding will be slowed down. New hair will grow after about 6 months of use. The best effect is within 1-2 years.

Therefore, when choosing oral finasteride, you must be under the guidance of a doctor and make sure it is androgenic alopecia before choosing it, and it must be 1mg finasteride, not 5mg finasteride.

Long-term use of 1 mg of finasteride can be effective for a long time. As the time of taking is extended, hair loss can remain stable for a long time and can be improved to the greatest extent. Then some patients may have mild adverse reactions during the medication process. The incidence of such adverse reactions does not exceed 2%. For most friends, as the medication time is prolonged, the adverse reactions will be relieved and eliminated on their own.

If there is no relief or elimination, it can be reversed after stopping the medication, so it is very safe. If patients with androgenic alopecia use it reasonably and consistently under the guidance of a doctor, their hair loss will be improved to the greatest extent, and the earlier it is used, the better the effect.

The effect of finasteride in treating hair loss will be more ideal for patients with androgenic alopecia with sparse hair on the top of the head, and the effect on the forehead is weaker than on the top of the head.

In the Long-Term Efficacy and Safety Study (PLESS), 3016 patients with moderate to severe symptoms of BPH who took this drug for 4 years were evaluated for BPH-related urinary tract management (surgical intervention), such as transurethral resection of the prostate and other prostatectomies, or acute urinary retention requiring insertion of a urinary catheter.

In this double-blind, randomized, placebo-controlled, multicenter study, treatment with the drug reduced the overall risk of urinary tract disposition by 51% and was associated with significant and sustained prostate volume reduction, as well as sustained increases in maximum urinary flow rate and symptomatic improvement.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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