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Rivaroxaban is the world's first oral direct factor Xa inhibitor, which can highly selectively and competitively inhibit free and bound factor It has the characteristics of high bioavailability, wide spectrum of disease treatment, stable dose-effect relationship, convenient oral administration and low risk of bleeding. Rivaroxaban is a drug that prevents and treats venous thrombosis. It is also used clinically to prevent the formation of deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients after hip and knee replacement surgery. It can also be used to prevent stroke and non-central nervous system embolism in patients with non-valvular atrial fibrillation, and reduce the risk of recurrence of coronary syndrome.

Rivaroxaban is a small molecule oral anticoagulant jointly developed by Bayer and Johnson & Johnson, with the trade name Xarelto. It obtained marketing approval in Canada and the European Union on September 15 and October 1, 2008 respectively. On July 1, 2011, the FDA approved the drug for the prevention of deep vein thrombosis in patients undergoing knee or hip replacement surgery.

Rivaroxaban is a prescription drug. It must be prescribed by a doctor according to the condition and taken according to the doctor's instructions. The recommended dose is: oral administration, 10 mg of rivaroxaban, once a day. If the wound has stopped bleeding, the first medication should be administered between 6 and 10 hours after surgery. Can be taken with food or alone. Rivaroxaban 15 mg or 20 mg should be taken with food.

Rivaroxaban is rapidly absorbed after oral administration. Peak concentration can be reached 2 to 4 hours after administration of 2.5 to 80 mg. It can be administered in multiple doses without accumulation within a reasonable range. It is eliminated in its original form by the kidneys and undergoes metabolic degradation. Multiple studies have shown that oral rivaroxaban has few interactions with food and drugs. It is currently a relatively safe and effective treatment method that does not require laboratory monitoring.