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Rivaroxaban has become a new oral anticoagulant drug with the widest range of clinical indications. As an effective and easy-to-administer single-drug regimen, it has a significant effect on the prevention and treatment of pulmonary embolism and deep vein thrombosis. It is expected to replace the standard treatment of deep vein thrombosis in the future. Today we will learn about the applicable groups of rivaroxaban.

The indications of rivaroxaban are: 1. Used in adult patients undergoing elective hip or knee replacement surgery to prevent venous thrombosis (VTE).

2. Used to treat venous thrombosis (DVT) in adults and reduce the risk of DVT recurrence and pulmonary embolism (PE) after acute DVT.

3. For use in adult patients with nonvalvular atrial fibrillation who have one or more risk factors (e.g., congestive heart failure, hypertension, age ≥75 years, diabetes, history of stroke or transient ischemic attack) to reduce the risk of stroke and systemic embolism.

Rivaroxaban is a small molecule oral anticoagulant jointly developed by Bayer and Johnson & Johnson, with the trade name Xarelto. It obtained marketing approval in Canada and the European Union on September 15 and October 1, 2008 respectively. On July 1, 2011, the FDA approved the drug for the prevention of deep vein thrombosis in patients undergoing knee or hip replacement surgery. Its chemical name is: 5-chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolin-5-yl)methyl)thiophene-2-carboxamide. Rivaroxaban is an oxazolidinone-derived selective FXa inhibitor that acts on the active site of factor

The recommended dose is oral rivaroxaban 10 mg once daily. If the wound has stopped bleeding, the first medication should be administered between 6 and 10 hours after surgery. The length of treatment is determined by each patient's risk of VTE, i.e. by the type of orthopedic surgery the patient has undergone. For patients undergoing major hip surgery, a recommended course of treatment is 5 weeks. For patients undergoing major knee surgery, a recommended course of treatment is 2 weeks. If a dose is missed, the patient should take rivaroxaban immediately and continue taking it once daily the next day. Patients can take rivaroxaban with a meal or on its own.

The above is the indications of rivaroxaban, I hope it can help you!